Fast, natural relief for joint pain

Joint pain can make you feel miserable.

Did you know that 1 in 3 adults suffers from joint pain, stiffness and swelling? Knee pain is the most common complaint, followed by shoulder and hip pain. 

There are lots of options out there that temporarily mask symptoms. But if you're trying to avoid NSAID medications and the associated side effects, there’s fast relief for people seeking natural solutions to the pain, stiffness, and impaired mobility of osteoarthritis and other joint issues.

NEM® Natural Eggshell Membrane is an innovative nutritional supplement clinically proven to reduce joint pain by 20% or more and best of all, it works within 7–10 days. Within one month, it's been proven to reduce pain by an average of 73%!  In recent clinical trials, NEM also reduced stiffness significantly, and improved range of motion.

In the long run, NEM provides continued support for joint health by reducing inflammation, improving flexibility, and protecting against the deterioration of cartilage. These one-a-day vegetarian capsules provide the same 500 mg dose of NEM used in clinical trials.

What is NEM?

NEM stands for natural eggshell membrane, the thin, fibrous membrane that lines the inside of the chicken eggshell (Gallus gallus) and separates it from the egg. This membrane is rich in nutrients that support the health of cartilage, connective tissue, and joints.

Why does NEM work so well? 

NEM is a natural source of type I collagen, glucosamine, chondroitin, hyaluronic acid, and calcium – which are the building blocks for healthy connective tissue and joints.

  • NEM supports the body’s production of type II collagen, the main component of the cartilage that covers our bones so that they move smoothly in joints without rubbing together.

  • NEM boosts production of chondroitin sulfate, another important component of cartilage, providing resistance to compression and contributing to cartilage, tendon, and ligament strength.

  • NEM contains glucosamine sulfate, which helps build cartilage and stimulates the production of the synovial fluid that lubricates the joints. NEM also contains hyaluronic acid, one of the main lubricants found in the synovial fluid.

  • The type I collagen in NEM helps reduce inflammation in the joints.

Osteoarthritis is a progressive degeneration of the joints caused by the gradual loss of cartilage, resulting in pain, stiffness, and loss of mobility. Many people use glucosamine and chondroitin for their joints, and they do provide relief, especially when used consistently. Long-term use of glucosamine may be more effective than analgesics and non-steroidal anti-inflammatory drugs (NSAIDs) for reducing joint pain, stiffness, and swelling.

However, we now know that we can do even better.  Glucosamine sulfate and NEM together reduce pain faster than glucosamine alone. NEM provides fast relief, while glucosamine works long term to protect and repair cartilage. Glucosamine sulfate stimulates cartilage formation and the production of synovial fluid. It also binds water inside the cartilage, improving its ability to absorb shocks.

Proven clinical results

For decades now, scientists have known that eggshell membrane contains collagen, glucosamine and other nutrients that support joint health. Exciting new research confirms that NEM can rapidly reduce joint pain and stiffness, without adverse side effects. In one of these studies, patients with mild to moderate joint pain received 500 mg of NEM daily. After just seven days, participants reported an average 26% improvement in pain and 28% improvement in flexibility. After 30 days, they had an average 73% reduction in pain, with 45% of participants reporting that they were completely pain free. They also had a 44% improvement in flexibility and 76% less pain through their range of motion.

A double-blind, placebo-controlled clinical trial involving patients with osteoarthritis of the knee produced similar results. After ten days, participants receiving NEM had an average 12% reduction in pain and 17% less stiffness. At the end of 60 days, those taking NEM had an average 15% reduction in pain and 31% less stiffness. Overall, one-third of the NEM patients experienced at least a 40% reduction in pain, and more than half had at least 50% less stiffness.


The NEM advantage:

  • Relieves joint pain and improves range of motion within 7–10 days

  • Helps protect and repair cartilage

  • Improves joint lubrication

  • Works effectively with glucosamine sulfate

  •  Relieves pain and inflammation without the potentially serious side effects of NSAIDs and other joint medications


Bruyere O, Reginster JY. Glucosamine and chondroitin sulfate as therapeutic agents for knee and hip osteoarthritis. Drugs Aging. 2007; 24(7):573-80.

Clegg DO, et al. Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis. N Engl J Med. 2006; 354(8):795-808.

Herrero-Beaumont G, et al. Glucosamine sulfate in the treatment of knee osteoarthritis symptoms. Arthritis Rheum. 2007; 56(2):555-567.

Ruff KJ, DeVore DP, Leu MD, et al. Eggshell membrane: a possible new natural therapeutic for joint and connective tissue disorders. Results from two open label human clinical studies. Clin Interv Aging. 2009; 4:235-40.

Ruff KJ, Winkler A, Jackson RW, et al. Eggshell membrane in the treatment of pain and stiffness from osteoarthritis of the knee: a randomized, multicenter, double-blind, placebo-controlled clinical study. Clin Rheumatol. 2009 Aug; 28(8):907-14.

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